Dual pathways found for centromere specification, ensuring accurate...
Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.
View ArticleNew DNA tests reveal hidden biological traces on Renaissance art
DNA analysis of cultural artifacts shows diverse biological profiles, but contamination and mixed signals complicate historical lineage interpretation.
View ArticleStudy uncovers how aggressive breast cancer cells escape immune defenses
With a new study in the journal Science Bulletin, researchers at Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University have discovered a new way that aggressive breast cancer cells escape the immune...
View ArticleNew insights into how a molecular gatekeeper controls early protein modification
For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have now discovered that this complex also contributes a crucial function in...
View ArticleResearchers discover the enzyme responsible for chromothripsis in cancer
University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled...
View ArticleShared genetic roots of 14 psychiatric disorders revealed
Researchers from the Psychiatric Genomics Consortium (PGC) report that most genetic influences on mental illness are shared across diagnostic categories, revealing a more interconnected biological...
View ArticleAustralian researchers pinpoint specific genetic changes linked to severe AMD
Australian researchers have for the first time pinpointed specific genetic changes that increase the risk of severe, sight-threatening forms of age-related macular degeneration (AMD).
View ArticleStudy reveals new genetic insights into reticular pseudodrusen in people with...
A study funded in part by the National Institutes of Health (NIH) has revealed important insights into the genetics of deposits in the eye, known as reticular pseudodrusen (RPD), that are linked to...
View ArticleA slow-growing, bone-covered, noncancerous mass named as ossifying spindled...
It's not often that a pathologist gets to make a diagnosis that works for the patient by preventing treatment from occurring.
View ArticleChemotherapy-free combination treatment outperforms traditional regimens in...
A chemotherapy-free combination treatment outperformed a combination of targeted therapy and chemotherapy among patients with Ph+ acute lymphoblastic leukemia (ALL) in a new study.
View ArticleY chromosome’s unexpected impact on aging and disease in men
Loss of the Y chromosome (LOY) in men, a dynamic mutation linked to aging, impairs immune function and increases risks of cancer, Alzheimer’s, and cardiovascular diseases, making it a promising...
View ArticleSimple blood tests for telomeric protein could provide a valuable screen for...
Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially...
View ArticlePathological significance of CEACAMS 1, 5, and 6 in cancer biology,...
A new review was published in Genes & Cancer on February 1, 2023, entitled, "CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens."
View Article3D architecture ofAedes aegypti’s chromosomes may offer clues on gene...
When it comes to DNA, one pesky mosquito turns out to be a rebel among species.
View ArticleNew blood test can detect prostate cancer with greater accuracy than current...
Researchers at the University of East Anglia have helped develop a new blood test to detect prostate cancer with greater accuracy than current methods.
View ArticleMicroscopic technique enables real-time study of RNA G-quadruplexes in living...
A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral sclerosis.
View ArticleStudy identifies the DNA roots of resistance to targeted cancer therapy
A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing...
View ArticlePersistent tumor mutation burden linked with therapeutic response to...
Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.
View ArticleCryo-electron microscopy reveals detailed blueprint of viral genome...
RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.
View ArticleStudy provides an estimate of people in the United States with VEXAS syndrome
About 13,200 men and another 2,300 women in the United States over age 50 are estimated to have VEXAS syndrome, according to a new study led by researchers at NYU Grossman School of Medicine.
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